Cellular immune response in virus infections

Evaluation of virus-specific cellular immune response in transplant patients.

Virus-specific immune responses have a major impact on the outcome of the infection. Viral agents that are characterized by latency, such as herpesviruses and polyomaviruses, require a continuous immune control to reduce the extent of viral reactivation, as viral clearance cannot be accomplished, independently from the anti-viral treatment. In transplant patients, morbidity and mortality relate...

Evaluation of Cellular Immune Response against Purified Antigen 85 in Patients with Tuberculosis

Background: Tuberculosis (TB) remains an important health problem throughout the world. Despite its significance in public health, mechanisms of protective immunity against Mycobacyerium Tuberculosis in humans have not yet been understood. Objective: To evaluate cell mediated immune response against purified Ag 85, PPD and Phytohemagglutinin (PHA) in patients with tuberculosis and healthy tuber...

cellular immune response following neonatal mice immunization with vesicular stomatitis virus

objective: infectious microorganisms are major sources of illness and death worldwide, and the leading cause of death in neonates. effective vaccination of this age group is of particular importance. the lack of a response and greater susceptibility to tolerance are two major features that limit the effectiveness of vaccines in neonates. in this study we compare the cellular immune response gen...

Immune response to fungal infections.

The immune mechanisms of defence against fungal infections are numerous, and range from protective mechanisms that were present early in evolution (innate immunity) to sophisticated adaptive mechanisms that are induced specifically during infection and disease (adaptive immunity). The first-line innate mechanism is the presence of physical barriers in the form of skin and mucous membranes, whic...

Immune responses in persistent virus infections.